Commentators agree that history records the following fulfilment of this further part of the prophecy: Antiochus III the Great now turned his attention elsewhere. He believed that the south, Egypt, was now secure through the marriage of his daughter, and he looked to ‘the isles’, a term used in Jewish history for not only the islands of the Mediterranean, but also its coasts – ‘and took many’.
In their fulfilment it is very clear what these prophecies meant, but so unexpected are the events and so mysterious is the language used, that it would have been hard to tell the meaning until the prophecy came to pass. Likewise, it would have been impossible to predict these events beforehand, especially from the distance that Daniel was shown them. No wonder Daniel has come under so much attack. The haters of God are faced with an irrefutable proof of the supernatural nature of the Bible. These things were prophesied right at the start of the previous empire. Man has enough experience of trying and failing to predict what will happen in just a limited area of life, for him to know that true prophecy hundreds of years ahead of time is the mark of the hand of God. The prophecy does not just speak of major powers and their influence, but seemingly small events which have a major effect on what happens. In some cases, the prophecy appears impossible until the fulfilment expounds it.