Here is how all the pagan lands and people of the region will become the property of Israel. ‘They of the south shall possess the mount of Esau; and they of the plains [shall possess] the Philistines: and they shall possess the fields of Ephraim’, and on it goes.
This has two simple applications. It ties in with the previous verse that over a period of time every nation of the world shall have the church of Jesus Christ represented in it, and Christ will save the Gentiles and people in every place. And then finally when the end shall come and all the unconverted are finally turned out of the world and into judgment, the people of God will even possess all the territory.