Solomon could mean one of two things. Is wine the mocker of us, or does it inspire us to be mockers of anything and everyone around us? In a sense, both are true, but here it is most likely that this is the effect that the intoxicating thing has on those who takes it: it makes them mockers.
But wine here is representative. It could be covetousness, possessions. Even a Christian may become possessive, wanting something too badly, thinking about it too much, longing after it too much. It becomes much too important to you and drives you, and you lose all sense of perspective and reason with regard to it, and the coveted thing must be obtained, and you pay any amount of effort to get it. Other example are power, the need for promotion, the need to be seen, to be better than other people. It is terrible if that gets hold of us. Some give much too much attention to appearances, and it gets hold of you and drives them. Or think of mood narcotics, if you like, that have a stupefying influence: as an example the relentless crashing beat of so much modern music, which people need and desperately depend upon as a mood lifter. It is the same effect as intoxicating liquor in a sense.
Social networking gets hold of people, and they become obsessed with it and cannot leave it alone or exercise any discipline or restraint on time. You may as well be drinking, it is the same effect. The mocking, the brawling (you will do anything to defend the practice), and then the staggering and the deception, the being misled by it. So you could apply it to all these things. It is very profound. Paul says, ‘I will not be brought under the power of any’ (1 Corinthians 6:12). That is the Christian standard.